Latest UpdateJune 22, 2025 - New variant information availableLearn More →

COVID Variants

Stay informed about the latest COVID-19 variants, their characteristics, and health implications. Information sourced from WHO, CDC, and ECDC databases, last updated: 2025-06-22.

Latest Update

NB.1.8.1 variant spreading rapidly across 22 countries, representing 10.7% of global sequences.Read full report →

NB.1.8.1

Medium RiskIncreasing
Variant Under Monitoring

Rapidly spreading descendant of XDV.1.5.1 with enhanced transmissibility mutations.

1.4x
Transmission Rate
65%
Vaccine Effectiveness
First detected: January 2025
Present in 22 countries

Common Symptoms

FeverCoughFatigueSore throatCongestion
Learn More

KP.3.1.1

Medium RiskDecreasing
Variant of Interest

Previously dominant variant in the US, now declining as new variants emerge.

1.3x
Transmission Rate
68%
Vaccine Effectiveness
First detected: March 2024
Present in 95 countries

Common Symptoms

CoughFatigueRunny noseHeadache
Learn More

XEC

Medium RiskIncreasing
Variant Under Monitoring

Hybrid recombinant of two JN.1 variants showing increased transmission.

1.5x
Transmission Rate
62%
Vaccine Effectiveness
First detected: August 2024
Present in 68 countries

Common Symptoms

CoughFatigueCongestionBody achesHeadache
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LP.8.1

Medium RiskStable
Variant Under Monitoring

Recently dominant globally but now declining as NB.1.8.1 increases.

1.2x
Transmission Rate
70%
Vaccine Effectiveness
First detected: February 2025
Present in 42 countries

Common Symptoms

Mild feverCoughFatigueSore throat
Learn More

KP.3

Medium RiskStable
Variant of Interest

Parent lineage of KP.3.1.1 with similar characteristics but lower prevalence.

1.3x
Transmission Rate
67%
Vaccine Effectiveness
First detected: January 2024
Present in 85 countries

Common Symptoms

CoughFatigueRunny noseBody aches
Learn More

MC.1

Medium RiskIncreasing
Variant Under Monitoring

Descendant of KP.3.1.1 showing gradual increase in circulation.

1.2x
Transmission Rate
69%
Vaccine Effectiveness
First detected: September 2024
Present in 28 countries

Common Symptoms

Mild symptomsCoughFatigueCongestion
Learn More

Understanding COVID Variants

What Are Variants?

COVID-19 variants are versions of the virus that have genetic changes. Some variants spread more easily, cause more severe illness, or reduce the effectiveness of treatments or vaccines.

Learn more about variants →

Stay Protected

Regardless of the variant, vaccination, masking, and good hygiene remain the best protection against COVID-19 and its variants.

View prevention guidelines →